Endocrine Abstracts

Objective: Changes in mood, appetite, dietary intakes and physic during a menstrual cycle has been controversial in studies. The aim of this study is to determine the nutritional behavior and body changes during the menstrual cycle in women of childbearing age by comparing dietary records and anthropometric measurements in three phases of menstrual cycle.Method: This prospective study included 34 healthy regularly menstruating women aged 20-39 years in A...

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

Seckel syndrome (SS) is a rare disorder of severe growth retardation and craniofacial-skeletal abnormalities. In scant number of reports, neonates had intact hypothalamic–pituitary–adrenal axis before they die because of cardiopulmonary abnormalities. We present an unique case of SS at the age of 18 years and discuss the possible explanations of his growth retardation and sex reversal.Case: A 18-year-old female presented with short stature and ...

Congenital adrenal hyperplasia (CAH) owing to 21 hydroxylase deficiency (21OHD) is an inherited autosomal disorder characterized by diminished glucocorticoid and aldosteron biosynthesis. Partial 21OHD leads to the classical simple virilizing form, characterized by prenatal virilization of external genitalia in female fetuses without salt wasting. Ambiguous genitalia in a genetically female infant is frequently due to CAH. The uncertainty about the sex of a newborn is often inc...

Native arteriovenous fistula (AVF) represents the best vascular approach for chronic hemodialysis. It is difficult to create an AVF in diabetic hemodialysis patients due to atherosclerotic changes in the arteries. Although AVF becomes useless after a successful kidney transplant, there is no accepted policy for preserving or ligating AVF. The aim of this study was to compare the fate of AVFs in diabetic and non-diabetic patients after kidney transplantation.<p class="abste...

Background: Acromegaly is a rare endocrine disorder characterized by sustained hypersecretion of growth hormone (GH) with concomitant elevation of insulin-like growth factor I (IGF-I) associated with acral enlargement, sleep apnea, cardiovascular and metabolic disorders. Its annual incidence is approximately six per million people. The most common cause of acromegaly is a somatotroph (growth hormone-secreting) adenoma of the anterior pituitary.Methods: A...

Aims: Medullary thyroid carcinoma (MTC) is a rare endocrine cancer that accounts for approximately 5% of all thyroid cancers. Both the diagnosis and management of MTC could be difficult. Surgery is a main therapy in MTC, chemotherapy and external radiotherapy have limited efficacy. Recently, the relationship between some of the hemocytometer parameters and cancer has been investigated. In this study we aimed to determine the relationship between MTC and hemocytometer parameter...

Thyroid acropachy is an uncommon and usually late complication of thyroid disease. The typical clinical presentation of thyroid acropachy includes clubbing, distal soft tissue swelling and periosteal reaction involving the tubular bones of the hands and feet. It is usually associated with exophthalmos and thyroid dermopathy. We present a case with thyroid acropachy as an initial manifestation of toxic adenoma.A 69-year-old man was admitted to our out-pat...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare, heritable syndrome characterized by a hyperparathyroidism, pituitary adenoma and pancreatic islet cells.Case: A 56-year-old male patient had a single parathyroid excised for primary hyperparathyroidism 10 years ago. He was further investigated due to hypoglycemia and a mass was found in the head of the pancreas on MRI. It was reported as neuroendocrine tumor and no recurrence was found i...

Introduction: Langerhans cell histiocytosis (LCH) is a neoplastic histiocytic disorder that characterized by proliferation of abnormal Langerhans cells. The most typical organs affected by LCH are the skin and bones, though it can also affect the pituitary gland, central nervous system, liver, spleen, lungs, and other organs.Case 1: 36 year old man presented with polyuria, polydipsia and right hip pain lasting about 4 months. The pain increased in the la...